- Proved in 1970 by Boffa and Dupin on 14 subjects, 7 men, and 7 women.
- The heart, blood and blood vessels were chiefly affected.
- Sleepiness during daytime.
- ChillyHypersensitive to cold temperaturesA constitutional state of feeling exceptionally cold, lacking vital heat, and needing warmth or heavy blankets..
- Worse left side.
- Nerves.
- Throbbing pains.
- Throbbing headache.
- Heavy sensation in eyes.
- Dazzling when raising eyes.
- Dryness of mouth, with pasty tongue, on waking in morning.
- Dry mouth before menses with small, very dark clots or with big red clots