# Alloxan

## Remedy Classification
- **Type:** Homeopathic Remedy
- **Miasm:** Tubercular Miasm
- **Temperament:** Hot
- **Aggravation Time:** Neutral/Anytime

## Keynote Indications
Alloxan was discovered accidentally by Dum and his collaborators in 1943. The toxicological 
action can be seen at the level of the pancreas, the kidneys, the liver, the lungs and in the blood. In animals, 
diabetes mellitus is provoked or, in other words, 
alloxanic diabetes. There would be a rapid degeneration if the islet Beta cells responsible for the production of 
insulin. 
The homeopathic proving of Alloxan was undertaken by Templeton on two occasions, in 1949 on six provers, 
when the potencies 6c and 30c were tried out, and in 1951 on nine provers and seven controls.  
Lack of heat and vital reaction. Disturbed sleep with nightmares. General indifference. Need for solitude. 
Dryness of digestive mu cus membranes. Diabetes mellitus.  Excessive thirst and frequent urination. Joint 
pains in the lumbar, sacral and ileocecal regions. Neuralgia of the tongue. Toothache. 
Acrid dyspepsia. Spontaneous ecchymosis and eruption of itching pimples. Sensation of body being dispersed 
into different parts. Osteoporosis and muscular weakness. Decrease of phosphoremia and increase of 
phosphates in the blood. Glycosuria without hyperglycemia.

## Modalities (Aggravations / Ameliorations)
Better from climbing stairs. 
Better closing eyes. Better eating, but if hungry, there is no improvement. Worse by dust, smells. Worse heat. 
Worse coughing. Worse laughter. Worse physical or mental exer tion. Worse noise. Worse left side. Worse 
between 4 p.m. and 5 p.m.

## Symptoms by System

### Mind
- Great forgetfulness.
- Forgets places, names, things just done, just heard.
- Loss of short -term memory.
- Spelling mistakes.
- Words don't register.
- Mistakes in spelling.
- Dyslexia.
- Silly mistakes in writing simple w ords.
- Silly sort of attitude to serious things.
- Alcoholic poly-neuritis with mental troubles.
- Paranoia.
- Sadness and tearfulness improved by solitude.
- Need 
for solitude and uneasiness about the future.
- Weeping better when alone.
- Indifference towards the sur rounding environment.
- Indifference to conversation.
- Indifference to loved ones.
- Indifference to work.
- Irritable with people, talking, loud voices.
- Irritability from noise.
- Fits of anger.
- Hurried.
- Dogmatic.
- Dictatorial.
- Impatient, taps foot with impatience.
- Quarrelsome.
- Hurried, others move too slow.
- Wants to dash about, wants 
to do everything quickly.
- Confusion as to his identity, as if head was being lifted off.
- Delusion, as if head were separated from body 
(Psor.).
- People talking seemed miles away.
- Voices seemed far away.
- Keeps washing hands.
- Great forgetfulness.
- Forgets places, names, things just done, just heard.
- Loss of short -term memory.
- Spelling mistakes.
- Words don't register.
- Mistakes in spelling.
- Dyslexia.
- Silly mistakes in writing simple w ords.
- Silly sort of attitude to serious things.
- Alcoholic poly-neuritis with mental troubles.
- Paranoia.
- Sadness and tearfulness improved by solitude.
- Need 
for solitude and uneasiness about the future.
- Weeping better when alone.
- Indifference towards the sur rounding environment.
- Indifference to conversation.
- Indifference to loved ones.
- Indifference to work.
- Irritable with people, talking, loud voices.
- Irritability from noise.
- Fits of anger.
- Hurried.
- Dogmatic.
- Dictatorial.
- Impatient, taps foot with impatience.
- Quarrelsome.
- Hurried, others move too slow.
- Wants to dash about, wants 
to do everything quickly.
- Confusion as to his identity, as if head was being lifted off.
- Delusion, as if head were separated from body 
(Psor.).
- People talking seemed miles away.
- Voices seemed far away.
- Keeps washing hands.

### Head
- Feeling of constriction and heat in the head, which is cold to the touch.
- Heaviness of head on waking 
with sensation of the hair being pulled.
- Headache better ascending steps, better closing eyes, worse couching, 
worse hot room.
- Headache from hunger, but eating does not relieve.
- Headache worse laughing, better talking, 
better travelling.
- Feeling of constriction and heat in the head, which is cold to the touch.
- Heaviness of head on waking 
with sensation of the hair being pulled.
- Headache better ascending steps, better closing eyes, worse couching, 
worse hot room.
- Headache from hunger, but eating does not relieve.
- Headache worse laughing, better talking, 
better travelling.

### Eyes
- Conjunctivitis.
- Eyelids red, burning and itching.
- Eyes painful, especially as a result of light and after 
reading, amelio rated by closing the lids.
- Sight dim with patches and bright spots.
- Myopia.
- Dim vision and 
twitching of eyelids, on waking (Cycl.).
- Sparks like fragments of fire.

### Ears
- Deep, drumming pain inside.
- Itching of the auditory canal.
- Eczema of the outer ear.

### Mouth
- Breath smells like apples.
- Salty taste on lips.
- Sweetish taste on lips.
- Cor ners of lips cracked.
- Dry, 
chapped lips.
- Lowerjaw painful.
- Toothache, aggravated by sweet things.
- Tip of  tongue painful.
- Small, superficial ulcers on the mouth and palate.
- Bitter, acrid taste, sweet taste on the lips.
- Mouth dry.
- Nose - Acute catarrh of the nasal mucus membrane with streaming, sometimes from the right side, sometimes 
from the left.
- Aggravated by dust, smells and heat.
- Catarrh from dust.
- Sensation of heat in nose on inspiration.
- Smell in nose as of musty books.

### Throat
- Acute and chronic laryngitis and pharyngitis.
- Dry, painful on the left side with burning, grating pain.
- Swallowing painful, improved with a hot drink.
- Throat pain better drinking, better expectoration, worse singing, 
when talking.

### Chest
- Feeling of a heavy weight on the chest.
- Heaviness better menses.
- Stitching pain better menses.
- Constitutions - The subjects are often phosphoric and very weak.
- Subjects nervous, uneasy, anxious.
- Pain as of a punch in the precordial region.
- Shooting pain in the heart, worse when walking.
- Retro -
sternal cramping pain.
- Cardiac neurosis.
- Kidneys - Kidney pain on the left side on uri nation.
- Dysuria.
- Glycosuria.
- Frothy urine, burning as it passes 
down the urethra.
- Frequent urination by day.
- Waking from urging to urinate, morbid desire.
- Sudden urging, 
can't hold urine for long.
- Breathing difficult after meals.

### Stomach & Abdomen
- Nausea before meals and heavy, aching feeling after.
- Nausea when travelling.
- Abdominal distention with profuse rumbling.
- Toxic diabetes.
- Ileocecal pain, aggravated by 
bending forwards and by movement.
- Sensation of a band around abdomen.
- Feeling of hunger, quickly sated.
- Hypogycemia.
- Aversion to salt.
- Desire for cold dritiks, refreshing 
things.
- Excessive thirst and feeling of dryness.
- Worse cold drinks, warm drinks.
- Better warm dri nks.

### Urinary & Genital
- Inflammation of the vulva and vagina.
- Feeling of swelling in the vagina, especially after standing for 
a long time.
- White leucorrhea, non-irritating, but increasing with the approach of menses.
- Sensation as if vagina 
were swollen, worse standing.

### Extremities
- Cramp in the calves and toes in bed.
- Aching with shivering in the arms, legs, ameliorated by stretching 
out, aggravated by the cold and by standing.
- Chronic joint problems.
- Chronic rheumatism of the hip.
- Heaviness 
and prominent veins in the legs.
- Varicose veins.
- Varicose hemorrhage.
- Itching of leg followed by ecchymoses.
- Numbness of arms when raising them.
- Numbness of legs when crossing them.
- Liver - Pain in liver on breathing, after eat ing, better eating, better pressure.
- Pulsat ing in liver.
- Bubbling in 
region of liver.

### Neck & Back
- Stiffness better stretching.
- Pain and c ervical stiffness, aggravated in bed, ameliorated by stretching.
- Cramping pain in the shoulder blade, cutting pain, aggravated by drinking.
- Lumbar rheumatism.
- Arthritis of the 
 
 
spine, preventing move ment.
- Pain in the lower lumbar region, worse in bed, in kneeling position and by 
standing, better by hot weather.
- Pain in lumbar region worse cold weather.
- Pain in lumbo -sacral region 
extending down legs.
- Bladder - Feeling of fullness in the bladder.
- Coldness in bladder, worse draft of air.
- Sensation as if bla dder is 
swollen.
- Incontinence on hurrying to get up, on sneezing.
- Bedwetting.
- Blood - Reduction in the number of phosphates in the blood plasma, normal presence of glucose in the blood, 
azotemia.
- Reduction of sedimentation rate.

### Skin
- Dry, cracking eczema.
- Ecchymosis.
- Rheumatoid purpura.
- Purpura without fever, beginning suddenly 
with large, benign ecchymoses.
- Hands dry, chapped.
- Spontaneous bruising of the fingers and legs.
- Skin dirty, 
with eruption of itching pimples.

### Sleep
- Troubled sleep with dreams, night mares.
- Sleepwalking, somnambulism.
- Insomnia until 2 a.m.
- Sleep 
disturbed by dreams.
- Dreams of accidents.
- Dreams being chased by a horse.
- Dreams of resurrection.
- Dreams 
of death of a friend.
- Dreams of bandits, robbers.
- Dreams of rats, toads, frogs in the bed.
- Dreams of being 
followed or falling.
- Dreams killing with a knife.
- Dreams being imprisoned.
- Dreams of sermons.