- Alloxan was discovered accidentally by Dum and his collaborators in 1943.
- The toxicological action can be seen at the level of the pancreas, the kidneys, the liver, the lungs and in the blood.
- In animals, diabetes mellitus is provoked or, in other words, alloxanic diabetes.
- There would be a rapid degeneration if the islet Beta cells responsible for the production of insulin.
- The homeopathic provingTesting a remedy on healthy volunteersThe systematic method of administering a substance to healthy subjects to observe and record the symptoms it produces. of Alloxan was undertaken by Templeton on two occasions, in 1949 on six provers, when the potencies 6c and 30c were tried out, and in 1951 on nine provers and seven controls.
- Lack of heat and vital reaction.
- Disturbed sleep with nightmares.
- General indifference.
- Need for solitude.
- Dryness of digestive mu cus membranes.
- Diabetes mellitus.
- Excessive thirst and frequent urination.
- Joint pains in the lumbar, sacral and ileocecal regions.
- NeuralgiaSharp nerve pain along a nerve pathIntense, shooting, or burning pain that radiates along the course of one or more nerves. of the tongue.
- Toothache.
- Acrid dyspepsiaIndigestion or upper abdominal discomfortDiscomfort or pain in the upper abdomen, often associated with nausea, bloating, heartburn, or acid reflux..
- Spontaneous ecchymosis and eruption of itching pimples.
- Sensation of body being dispersed into different parts.
- Osteoporosis and muscular weakness.
- Decrease of phosphoremia and increase of phosphates in the blood.
- Glycosuria without hyperglycemia